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EpiX Technology

General
Airway Tissues
Skin Tissues

CR Technology

General
Airway Tissues
Head, Neck, Glandular & GI Tract Tissues
Mammary & Prostate Tissues
Oncology Applications

Patient-Derived Conditionally Reprogrammed Cells Maintain Intra-Tumor Genetic Heterogeneity. Correa BRS, Hu J, Penalva LOF, Schlegel R, Rimm DL, Galante PAF, Agarwal S. (2018) Sci Rep. Mar 6;8(1):4097. PMID: 29511269

Expanding Primary Cells From Mucoepidermoid And Other Salivary Gland Neoplasms For Genetic And Chemosensitivity Testing. Alamri AM, Liu X, Blancato JK, Haddad BR, Wang W, Zhong X, Choudhary S, Krawczyk E, Kallakury BV, Davidson BJ, Furth PA. (2018) Dis Model Mech. Jan 29;11(1). PMID: 29419396

Characterization Of The Effects Of Defined, Multidimensional Culture Conditions On Conditionally Reprogrammed Primary Human Prostate Cells. Tricoli L, Naeem A, Parasido E, Mikhaiel JP, Choudhry MU, Berry DL, Abdelgawad IA, Lee RJ, Feldman AS, Ihemelandu C, Avantaggiati M, Kumar D, Byers S, Gallagher R, Wulfkuhle J, Petricoin E, Rodriguez O, Albanese C. (2017) Oncotarget. Dec 18;9(2):2193-2207. PMID: 29416764

Generation Of Stable PDX Derived Cell Lines Using Conditional Reprogramming. Borodovsky A, McQuiston TJ, Stetson D, Ahmed A, Whitston D, Zhang J, Grondine M, Lawson D, Challberg SS, Zinda M, Pollok BA, Dougherty BA, D'Cruz CM. (2017) Mol Cancer. Dec 6;16(1):177. PMID: 29212548

Genomic Comparison Of Early-Passage Conditionally Reprogrammed Breast Cancer Cells To Their Corresponding Primary Tumors. Mahajan AS, Sugita BM, Duttargi AN, Saenz F, Krawczyk E, McCutcheon JN, Fonseca AS, Kallakury B, Pohlmann P, Gusev Y, Cavalli LR. (2017) PLoS One. Oct 19;12(10):e0186190. PMID: 29049316

Emerging Opportunities For Target Discovery In Rare Cancers. Sharifnia T, Hong AL, Painter CA, Boehm JS. (2017) Cell Chem Biol. Sep 21;24(9):1075-1091. Review. PMID: 28938087

A Multiplex Preclinical Model For Adenoid Cystic Carcinoma Of The Salivary Gland Identifies Regorafenib As A Potential Therapeutic Drug. Chen C, Choudhury S, Wangsa D, Lescott CJ, Wilkins DJ, Sripadhan P, Liu X, Wangsa D, Ried T, Moskaluk C, Wick MJ, Glasgow E, Schlegel R, Agarwal S. (2017) Sci Rep. Sep 12;7(1):11410. PMID: 28900283

Comprehensive Drug Testing Of Patient-Derived Conditionally Reprogrammed Cells From Castration-Resistant Prostate Cancer.Saeed K, Rahkama V, Eldfors S, Bychkov D, Mpindi JP, Yadav B, Paavolainen L, Aittokallio T, Heckman C, Wennerberg K, Peehl DM, Horvath P, Mirtti T, Rannikko A, Kallioniemi O, Östling P, Af Hällström TM. (2017) Eur Urol. Mar;71(3):319-327. PMID: 27160946

A Rapid Filter Insert-Based 3D Culture System For Primary Prostate Cell Differentiation. Tricoli L, Berry DL, Albanese C. (2017) J Vis Exp. Feb 13;(120). PMID: 28287583

Conditional Reprogramming And Long-Term Expansion Of Normal And Tumor Cells From Human Biospecimens. Liu X, Krawczyk E, Suprynowicz FA, Palechor-Ceron N, Yuan H, Dakic A, Simic V, Zheng YL, Sripadhan P, Chen C, Lu J, Hou TW, Choudhury S, Kallakury B, Tang DG, Darling T, Thangapazham R, Timofeeva O, Dritschilo A, Randell SH, Albanese C, Agarwal S, Schlegel R. (2017) Nat Protoc. Feb;12(2):439-451. PMID: 28125105

Conditionally Reprogrammed Normal And Transformed Mouse Mammary Epithelial Cells Display A Progenitor-Cell-Like Phenotype. Saenz FR, Ory V, AIOtaiby M, Rosenfield S, Furlong M, Cavalli LR, Johnson MD, Liu X, Schlegel R, Wellstein A, Riegel AT  PLoS ONE 9(5):e97666. PMID: 24831228

Screening Of Conditionally Reprogrammed Patient-Derived Carcinoma Cells Identifies ERCC3-MYC Interactions As A Target In Pancreatic Cancer. Beglyarova N, Banina E, Zhou Y, Mukhamadeeva R, Andrianov G, Bobrov E, Lysenko E, Skobeleva N, Gabitova L, Restifo D, Pressman M, Serebriiskii IG, Hoffman JP, Paz K, Behrens D, Khazak V, Jablonski SA, Golemis EA, Weiner LM, Astsaturov I (2016) Clin Cancer Res Treat 22(24):6153-6163. PMID: 27384421

Conditionally Reprogrammed Normal And Primary Tumor Prostate Epithelial Cells: A Novel Patient-Derived Cell Model For Studies Of Human Prostate Cancer. Timofeeva OA, Palechor-Ceron N, Li G, Yuan H, Krawczyk E, Zhong X, Liu G, Upadhyay G, Dakic A, Yu S, Fang S, Choudhury S, Zhang X, Ju A, Lee MS, Dan HC, Ji Y, Hou Y, Zheng YL, Albanese C, Rhim J, Schlegel R, Dritschilo A, Liu X  (2016) Oncotarget 10.18632/oncotarget.13937. PMID: 28009986

An Ecosystem Of Cancer Cell Line Factories To Support A Cancer Dependency Map. Boehm JS, Golub TR (2015) Nat Rev Genet 16: 373-374. PMID: 26077369

Developing In Vitro Models Of Human Ductal Carcinoma In Situ From Primary Tissue Explants. Brown DD, Dabbs DJ, Lee AV, McGuire KP, Ahrendt GM, Bhargava R, Davidson NE, Brufsky AM, Johnson RR, Oesterreich S, McAuliffe PF (2015) Breast Cancer Res Treat 153(2):311-21. PMID: 26283301

Patient-Derived Models Of Acquired Resistance Can Identify Effective Drug Combinations For Cancer. Crystal AS, Shaw AT, Sequist LV, Friboulet L, Niederst MJ, Lockerman EL, Frias RL, Gainor JF, Amzallag A, Greninger P, Lee D, Kalsy A, Gomez-Caraballo M, Elamine L, Howe E, Hur W, Lifshits E, Robinson HE, Katayama R, Faber AC, Awad MM, Ramaswamy S, Mino-Kenudson M, Iafrate AJ, Benes CH, Engelman JA (2014) Science 346(6216):1480-1486. PMID: 25394791

Use Of Reprogrammed Cells To Identify Therapy For Respiratory Papillomatosis. Yuan H, Myers S, Wang J, Zhou D, Woo JA, Kallakury B, Ju A, Bazylewicz M, Carter YM, Albanese C, Grant N, Shad A, Dritschilo A, Liu X, Schlegel R (2012) New Engl J Med 367(13):1220-1227. PMID: 23013073